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Dr. Niki Smith Dr. Niki Smith

Why Skipping Breakfast Backfires in Perimenopause, PMDD, and ADHD

Dopamine and serotonin are synthesized from amino acids. Hormones are synthesized from cholesterol and require adequate energy availability. When food intake is delayed, amino acid availability decreases. This does not mean neurotransmitters stop being produced. But prolonged energy restriction reduces substrate availability for optimal synthesis.

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Dr. Niki Smith Dr. Niki Smith

ADHD and Blood Sugar

ADHD is often explained as a dopamine issue. But attention, mood, and focus are also influenced by physiology. The brain depends on stable energy. This article explores how glucose regulation, stress physiology, hormones, and energy availability interact with attention.

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Dr. Niki Smith Dr. Niki Smith

Is Black Cohosh a BFF for Your Hormones?

Black cohosh (Actaea racemosa, formerly Cimicifuga racemosa) is not a trendy hormone hack or a one-size-fits-all solution. It is a clinically relevant medicinal plant with a long history of traditional use, a surprisingly complex mechanism of action, and research that looks inconsistent mainly because quality, dosing, and preparation matter far more than most people realize (Braun & Cohen, 2024; Wuttke et al., 2014).

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Dr. Niki Smith Dr. Niki Smith

From Symptoms to Strategy: Why I Start With Labs

This is one of the most common frustrations I hear in practice. And it is exactly why I do not start with protocols. I start with labs. Not because labs are trendy or because more data is always better, but because guessing, even educated guessing, often leads people further away from relief instead of closer to it.

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Dr. Niki Smith Dr. Niki Smith

Why PMDD Doesn’t Always Improve With Age or Menopause

PMDD is often framed as a hormone problem. But the reality is more complex. For many individuals, PMDD is not driven by abnormal hormone levels. It is driven by how the brain and nervous system respond to normal hormonal shifts. That distinction matters, especially as we move through different life stages.

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Dr. Niki Smith Dr. Niki Smith

Why Lab Timing Matters More Than Supplements

For ADHD, Hormonal Symptoms, and Chronic Stress. This experience is frustrating, and it is also incredibly common. It often leads people to assume that supplements do not work, or that their body is unusually sensitive or resistant to support. In most cases, neither is true. More often, the issue is timing, physiological context, and unmet demand, not the supplement itself.

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Dr. Niki Smith Dr. Niki Smith

Vyvanse, Supplements, and “Safe” Nutrients

Vyvanse (lisdexamfetamine dimesylate) is one of the most commonly prescribed stimulant medications for ADHD. It is also FDA approved for moderate to severe binge eating disorder in adults. For many people, it plays an important role in improving focus, task completion, impulse control, and daily functioning. But there is a major gap in how this medication is typically discussed.

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Dr. Niki Smith Dr. Niki Smith

Vitamin B3 (Niacin)

Vitamin B3, also known as niacin, is rarely part of conversations about mental health. When it is mentioned, it is usually framed as a cholesterol-lowering nutrient or the vitamin known for causing uncomfortable flushing at high doses.

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Dr. Niki Smith Dr. Niki Smith

How Gut Dysbiosis Affects ADHD Symptoms: What the Science Really Shows

If you’ve ever noticed that your (or your child’s) ADHD symptoms flare with digestive issues, inflammation, or after antibiotics, you’re not imagining it. A growing body of science shows that gut dysbiosis—an imbalance in gut bacteria—can directly influence ADHD traits like impulsivity, hyperactivity, emotional dysregulation, reward-seeking, and even anxiety.

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Dr. Niki Smith Dr. Niki Smith

Rosemary: The Herb for Focus, Gut Health, and Antioxidant Power

Rosemary has been celebrated for centuries for sharpening memory and awakening the senses. Today, research confirms that this piney Mediterranean herb supports brain health, gut balance, and antioxidant defense — three pillars I focus on in my work with ADHD, fatigue, and hormone imbalance.

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Dr. Niki Smith Dr. Niki Smith

Functional Lab Testing for PMDD

If you live with PMDD (Premenstrual Dysphoric Disorder), you already know it’s not “just PMS.” PMDD can feel like your hormones and emotions are waging war against you—every single month. Mood swings, fatigue, irritability, and low motivation can make it hard to focus, work, or even feel like yourself.

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Dr. Niki Smith Dr. Niki Smith

Tired, Foggy, and Unfocused?

If you’ve ever felt like your ADHD symptoms flare with fatigue, brain fog, irritability, or even depression, you’re not imagining it. Research increasingly shows that low iron levels and anemia can both mimic and amplify ADHD symptoms, affecting focus, energy, and emotional balance.

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Dr. Niki Smith Dr. Niki Smith

ADHD in Women

This is why ADHD in women is so often misunderstood. For decades, research focused on young boys. Girls and women slipped through the cracks, misdiagnosed with anxiety or depression, told to “just try harder.” Meanwhile, their ADHD symptoms were actually being supercharged by estrogen changes and inflammation.

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Dr. Niki Smith Dr. Niki Smith

Why Impulsivity Isn’t Just “Bad Behavior”

Have you ever found yourself blurting something out and regretting it right away? Or maybe you made a purchase you couldn’t really afford, snapped at your partner, or grabbed junk food even when you swore you’d eat better? Most people chalk these up to “bad habits” or “lack of willpower.” But research is uncovering something shocking: inflammation can literally rewire how your brain makes decisions — pushing you toward impulsivity and poor self-control.

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Dr. Niki Smith Dr. Niki Smith

Vitex and PMDD

If you’ve ever felt like your hormones hijack your life every single month, you’re not alone. For women with PMDD (premenstrual dysphoric disorder), those days before a period can bring crushing mood swings, irritability, depression, and physical symptoms that feel impossible to manage. While conventional treatments often focus on birth control or antidepressants, many women are searching for natural options that address the root cause. That’s where Vitex (Vitex agnus-castus), also known as chasteberry, comes in.

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Dr. Niki Smith Dr. Niki Smith

PMDD and Progesterone: What’s the Catch?

Premenstrual dysphoric disorder (PMDD) is more than “bad PMS.” It affects up to 29% of women of reproductive age and can completely disrupt daily life. PMDD symptoms often appear in the two weeks before a period and may include rage, depression, brain fog, exhaustion, and even suicidal thoughts.

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Dr. Niki Smith Dr. Niki Smith

PMDD, Histamine, and the Bigger Picture

If you’ve spent time in PMDD support groups or scrolling through TikTok lately, you’ve probably seen people talking about histamine. Some women say that popping an antihistamine like Benadryl or Zyrtec takes the edge off their luteal phase symptoms. Others swear by natural antihistamines like quercetin or vitamin C.

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Dr. Niki Smith Dr. Niki Smith

Lead and ADHD

If you have ADHD, or parent a child with ADHD, here’s a truth bomb you probably haven’t heard from your pediatrician: Heavy metals, especially lead, can make ADHD symptoms up to 20% worse.

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Dr. Niki Smith Dr. Niki Smith

Why Choline Deserves a Spot in Your Child's ADHD Care Plan

Choline is a water-soluble nutrient often grouped with the B-vitamin family. It’s critical for brain development, neurotransmitter production, and maintaining healthy cell membranes. In fact, it’s a key building block for acetylcholine, a neurotransmitter that influences memory, attention, and muscle control — all areas that kids with ADHD may struggle with.

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Struggling with ADHD or PMDD and tired of being told to just deal with it”?

This group is your safe space to finally get answers. Root Cause Relief for ADHD & PMDD goes beyond surface-level fixes to uncover what’s really driving your symptoms, nutritional imbalances, gut health, hormones, and more.

This community offers evidence-based strategies, holistic tools, and compassionate support. If you’re ready for clarity, calm, and real relief, you belong here.